Complex Regional Pain Syndrome (CRPS) is a chronic pain condition that usually develops after an injury, surgery, or trauma affecting a limb. The condition causes intense, persistent pain that may feel burning, throbbing, or hypersensitive to touch. CRPS can also lead to swelling, temperature changes, and reduced movement in the affected area. In some cases, the original injury may appear to have healed while pain continues to interfere with everyday activities.
LeafEase offers individuals living with complex regional pain syndrome the opportunity to explore regulated medical cannabis treatment when conventional pain management strategies have not provided sufficient relief.
of complex regional pain syndrome cases occur after trauma or surgery affecting a limb.
of people diagnosed with complex regional pain syndrome are women.
5–26 people per 100,000 in the UK develop complex regional pain syndrome each year.
Symptoms often develop in the affected limb and may gradually spread to surrounding areas.
If these symptoms sound familiar and continue despite usual treatments, you can quickly check your eligibility for medical cannabis treatment through LeafEase’s simple online assessment.
In the UK, treatment for complex regional pain syndrome usually begins with physiotherapy, rehabilitation exercises, and pain management strategies designed to maintain mobility and reduce nerve sensitivity.
Lifestyle adjustments and therapies aimed at improving circulation and muscle movement are also commonly recommended. For some individuals, severe pain and nerve sensitivity may persist despite these approaches.
When symptoms remain difficult to manage through conventional care, medical cannabis may offer an alternative option under specialist supervision. At LeafEase, patients undergo a clinical assessment to determine treatment suitability and receive ongoing monitoring to support safe and effective symptom management.
Complex regional pain syndrome is believed to involve abnormal responses within the nervous system following injury or trauma. The condition may develop when nerve signals continue to trigger pain responses even after the original injury has healed.
This condition often affects a single limb, such as the arm, hand, leg, or foot.
Changes in inflammation, circulation, and nerve signalling may contribute to the development of CRPS.
Find out if you may be eligible for Complex Regional Pain Syndrome medical cannabis treatment here.
Medical cannabis interacts with the body’s endocannabinoid system, which regulates pain perception, inflammation, and nerve activity. The cannabinoids THC (tetrahydrocannabinol) and CBD (cannabidiol) influence pathways involved in chronic nerve-related pain.
THC helps reduce pain perception and supports improved sleep, while CBD provides anti-inflammatory effects and helps regulate nerve signalling associated with chronic pain conditions. In the UK, specialist clinicians prescribe and supervise medical cannabis treatment to ensure safe and appropriate use.
Reference: https://pubmed.ncbi.nlm.nih.gov/40898690/
Reference: https://clinicaltrials.ucsd.edu/trial/NCT06393101
At LeafEase, treatment is delivered under specialist supervision, ensuring every patient is safely assessed and supported throughout their care. Our personalised approach helps you explore medical cannabis as a regulated, clinically guided option for long-term pain relief.
Medical cannabis treatment is generally well tolerated when used under specialist supervision. Some individuals may notice mild effects as their body adjusts to treatment.
These effects are usually mild and often improve as treatment is adjusted. Regular clinical reviews help ensure treatment remains safe and suitable.
Find out whether medical cannabis may be a suitable treatment option for Complex Regional Pain Syndrome
Simply submit your questions, and we’ll do our best to address them promptly and thoroughly. Your health is our priority, and we’re here to support you every step of the way.
Medical cannabis may help regulate nerve-related pain signals and inflammation associated with CRPS, which may improve comfort and sleep for some individuals.
Specialist clinicians in the UK may prescribe medical cannabis for chronic pain conditions when conventional treatments have not provided adequate symptom relief.
Medical cannabis may help manage symptoms such as severe nerve pain, burning sensations, swelling, and sleep disturbance linked to complex regional pain syndrome.
Cannabinoids interact with receptors involved in pain signalling and inflammation, which may help regulate abnormal nerve responses associated with CRPS.
At LeafEase, patients undergo a specialist clinical assessment where symptoms, medical history, and previous treatments are reviewed to determine whether regulated medical cannabis treatment may be appropriate.
